Sailor Pluto was the first Senshi form Setsuna fought in and was able to transform into. She was shown fighting in her Senshi fuku in the R season of the anime or the Black Moon arc in the manga, able to transform into Sailor Pluto in the S season of the anime or the Infinity arc in the manga, and once in the Stars season before her Super upgrade.

As Sailor Pluto, she wore the standard Senshi fuku and the dominant color of the fuku was black while the accent colors were garnet and dark maroon. Her choker, collar, the elbow fittings on her gloves, her skirt, and boots were black, her tiara gem, earrings, and the gem on her choker were garnet, and her front and back bows were dark maroon. Her earrings were shaped like thick down-pointing arrows, her collar did not have any stripes, her choker had a garnet gem dangling from it, and she was the only Sailor Senshi not to have shoulder pads with her fuku. Her boots were similar to those of Sailor Moon's and Sailor Mercury's.

The anime version was very similar to the manga version, except in the manga, she had a chain around her waist that held many keys on it, and after her reincarnation (as she died in the Black Moon arc after breaking the most sacred taboo), the center of her front bow was black instead of garnet.

In the musicals, Sailor Pluto's fuku was significantly different from the manga and anime versions. Instead of garnet as one of the main colors of her fuku, her fuku colors were mainly blue, black and purple. Her collar and skirt's top layer were a dark blue, and the bottom layer of her skirt was purple. Both her front and back bows, her boots, and her elbow fittings were black. Early versions of her costume had gold trim, while later versions had silver trim, and her collar had two stripes, unlike the anime and manga versions.

Super Sailor Pluto was the second form and the last form in the anime Setsune was able to transform into. She transformed into this form in the Sailor Stars season of the anime, and the Yume/Dream arc of the manga.

In the manga, when Sailor Moon transformed into Super Sailor Moon for the first time, her brooch became a heart, but she did not receive the Super upgrade until towards the end of the Infinity arc.

In the anime, when she received the Super upgrade, her choker had a gold star attacked to it, her collar only had one stripe, the center of her front bow became a heart, the bottom of her shoulder pads became translucent, and back bow became larger and was lengthened.

The anime version was similar to the manga version, except in the manga, the star on her choker had a garnet gem on it.

During the Silver Millennium, Sailor Pluto was also the Princess of her home world. She was among those given the duty of protecting the solar system from outside invasion. As Princess Pluto, she dwelt in Charon Castle and wore a black gown—she appears in this form in the original manga Act 41, as well as in supplementary art.

After being killed by Sailor Galaxia in Act 49 of the Stars manga, Sailor Pluto is revived by her and brainwashed and ordered to kill Eternal Sailor Moon. Once revived she wears her Eternal fuku with bracelets similar to the ones Galaxia wears. The bracelets are gold with a gem on each bracelet, one purple and one green.

This form only appeared in the manga.

Eternal Sailor Pluto was the third and final form Setsuna was able to transform into in the StarS arc of the manga. She never transformed into this form in the anime.

After the last upgrade in the Stars arc, her choker was V-shaped and the center of her front bow was a gray five-pointed star. Her shoulder pads were large gray puffs with two patches of black fabric attached to the bottom. Her gloves became longer, reaching to her upper arms. Her belt consisted of two ribbons - one black and one gray, with two long, thin back ribbons, clipped together by a golden five-pointed star. Her back bow was gray. Her skirt became two-layered, the top layer being black and the bottom layer gray. Her boots were knee-length and white, and each had a black V-shaped border with a five-pointed star at the top. Her tiara gem was a black five-pointed star and her earrings were black, dangling five-pointed stars.