Hailing from 30th century Crystal Tokyo, they are all recruited by Shaman Apsu and given powers equal to their counterparts. Each girl has their own motives for joining, as does Apsu who is rapidly dying from existing in the Crystal Tokyo era. Oppositio is the Latin for opposition, and they are named after Babylonian gods. Each of them have their own attacks, or have another attack from another villain.
- Sin - opposed to Sailor Moon
- Nabu - opposed to Sailor Mercury
- Nergal - opposed to Sailor Mars
- Marduk - opposed to Sailor Jupiter
- Ishtar - opposed to Sailor Venus
- The term "Opposito" is a play on the English word "opposite".